Table 4 Patient Demographics for Cohort 2.

From: A fragment of type VI collagen alpha-6 chain is elevated in serum from patients with atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus and melanoma

 

Healthy donors (n = 22)

Atopic dermatitis (n = 158)

p

Males, n (%)

11 (50%)

82 (52%)

0.827

Age at sampling, mean (range)

29.6 (6.0–65.0)

30.0 (4.3–90.9)

0.902

SCORAD, n 

Mild (< 25)

Moderate (25–50)

Severe (> 50)

 

53 (33.5%)

72 (45.6%)

33 (20.9%)

 

Itch (VAS)

 

5.7 (5.6)

 

Sleep Impact (VAS)

 

3.1 (3.2)

 

FLG-mutation (R2447X, R501X and 2282del4)

 

33 (20.9%)

 

Asthma

 

74 (46.8%)

 

Allergic rhinoconjunctivitis

 

89 (56.3%)

 

Urticaria

 

64 (40.5%)

 

Food Allergy

 

84 (53.2%)

 

Eosinophil count (× 109/L)

 

0.43 (0.43)

 

Serum total IgE (103 IU/L)

 

1,282.3 (2,088.8)

 

Systemic treatments 

Cyclosporine, n (%)

Methotrexate, n (%)

Prednisolone, n (%)

Azathioprine, n (%)

Number of pts on systemic treatment, n (%)

 

2 (1.2%)

2 (1.2%)

29 (18.4%)

14 (8.9%)

37 (23.4%)

 
  1. Categorical variables are written as number (percentage), while continuous variables are mean (standard deviation). SCORAD, SCORing Atopic Dermatitis; FLG, Filaggrin gene; VAS, visual analogue scale; pts, Patients.
Back to article page