Table 3 Impact of age and illness duration on miRNA expression.
miRNA (relative expression) | ME/CFS | ME/CFS + FM | FM | HC | |||
|---|---|---|---|---|---|---|---|
Age (years) | Illness duration (years) | Age (years) | Illness duration (years) | Age (years) | Illness duration (years) | Age (years) | |
Hsa-miR-28-5p | r = 0.062 | r = 0.196 | r = − 0.033 | r = − 0.070 | r = 0.017 | r = 0.069 | r = − 0.286 |
p = 0.700 | p = 0.219 | p = 0.865 | p = 0.728 | p = 0.917 | p = 0.717 | p = 0.113 | |
Hsa-miR-29a-3p | r = 0.179 | r = 0.146 | r = 0.199 | r = 0.181 | r = − 0.063 | r = 0.092 | r = 0.040 |
p = 0.262 | p = 0.364 | p = 0.300 | p = 0.367 | p = 0.706 | p = 0.630 | p = 0.830 | |
Hsa-miR-127-3p | r = 0.035 | r = − 0.023 | r = 0.218 | r = 0.094 | r = 0.000 | r = − 0.056 | r = − 0.299 |
p = 0.825 | p = 0.886 | p = 0.256 | p = 0.642 | p = 0.999 | p = 0.768 | p = 0.096 | |
Hsa-miR-140-5p | r = 0.136 | r = 0.137 | r = − 0.294 | r = 0.000 | r = − 0.028 | r = 0.124 | r = − 0.262 |
p = 0.395 | p = 0.394 | p = 0.122 | p = 0.999 | p = 0.870 | p = 0.513 | p = 0.147 | |
Hsa-miR-150-5p | r = 0.002 | r = − 0.087 | r = − 0.237 | r = − 0.108 | r = − 0.061 | r = − 0.005 | r = − 0.116 |
p = 0.989 | p = 0.588 | p = 0.216 | p = 0.591 | p = 0.717 | p = 0.981 | p = 0.527 | |
Hsa-miR-181b-5p | r = − 0.120 | r = − 0.161 | r = − 0.167 | r = − 0.254 | r = − 0.170 | r = − 0.004 | r = − 0.173 |
p = 0.454 | p = 0.315 | p = 0.388 | p = 0.200 | p = 0.307 | p = 0.982 | p = 0.344 | |
Hsa-miR-374b-5p | r = 0.136 | r = 0.043 | r = 0.177 | r = − 0.025 | r = − 0.024 | r = 0.131 | r = − 0.061 |
p = 0.396 | p = 0.789 | p = 0.358 | p = 0.902 | p = 0.888 | p = 0.491 | p = 0.740 | |
Hsa-miR-486-5p | r = 0.278 | r = 0.129 | r = 0.325 | r = 0.262 | r = − 0.115 | r = 0.014 | r = − 0.208 |
p = 0.078 | p = 0.423 | p = 0.085 | p = 0.188 | p = 0.492 | p = 0.943 | p = 0.253 | |
Hsa-miR-3620-3p | r = − 0.244 | r = − 0.161 | r = 0.141 | r = 0.292 | r = − 0.148 | r = 0.085 | r = − 0.032 |
p = 0.125 | p = 0.314 | p = 0.465 | p = 0.139 | p = 0.375 | p = 0.655 | p = 0.863 | |
Hsa-miR-4433a-5p | r = 0.066 | r = − 0.093 | r = 0.006 | r = − 0.364 | r = 0.132 | r = 0.084 | r = 0.032 |
p = 0.680 | p = 0.562 | p = 0.976 | p = 0.062 | p = 0.429 | p = 0.658 | p = 0.861 | |
Hsa-miR-6819-3p | r = − 0.073 | r = − 0.053 | r = − 0.160 | r = − 0.174 | r = − 0.304 | r = 0.027 | r = 0.053 |
p = 0.651 | p = 0.742 | p = 0.409 | p = 0.385 | p = 0.064 | p = 0.887 | p = 0.773 | |
