Table 4 Correlation between 11 miRNAs and different symptoms in ME/CFS, ME/CFS + FM and FM groups.
SF-36 | MFI-20 | DSQ | CARTaGENE | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Physical score | Mental score | General fatigue | Physical fatigue | Reduced activity | Reduced motivation | Mental fatigue | Autonomic neuro-endocrine immune | Cognitive | Post exertional malaise | Sleep | Muscles pain | Joints pain | Total pain occurrence | |
ME/CFS miRNA expression | ||||||||||||||
miR-150-5p | r = − 0.322 | r = − 0.014 | r = 0.206 | r = 0.146 | r = 0.013 | r = 0.043 | r = 0.198 | r = 0.416 | r = 0.185 | r = 0.318 | r = 0.288 | r = 0.355 | r = 0351 | N/A |
p = 0.040 | p = 0.932 | p = 0.196 | p = 0.363 | p = 0.937 | p = 0.790 | p = 0.215 | p = 0.007 | p = 0.247 | p = 0.043 | p = 0.068 | p = 0.023 | p = 0.024 | ||
miR-3620-3p | r = 0.078 | r = 0.312 | r = − 0.060 | r = 0.020 | r = − 0.012 | r = − 0.116 | r = 0.070 | r = − 0.268 | r = − 0.317 | r = 0.034 | r = − 0.338 | r = − 0.076 | r = − 0.123 | N/A |
p = 0.627 | p = 0.047 | p = 0.710 | p = 0.899 | p = 0.938 | p = 0.470 | p = 0.662 | p = 0.091 | p = 0.043 | p = 0.834 | p = 0.031 | p = 0.636 | p = 0.443 | ||
miR-6819-3p | r = 0.122 | r = 0.333 | r = − 0.143 | r = − 0.113 | r = − 0.206 | r = − 0.269 | r = − 0.069 | r = − 0.077 | r = − 0.199 | r = − 0.016 | r = − 0.149 | r = 0.041 | r = 0.014 | N/A |
p = 0.448 | p = 0.033 | p = 0.374 | p = 0.483 | p = 0.197 | p = 0.090 | p = 0.667 | p = 0.631 | p = 0.211 | p = 0.922 | p = 0.353 | p = 0.800 | p = 0.930 | ||
ME/CFS + FM miRNA expression | ||||||||||||||
miR-150-5p | r = 0.233 | r = − 0.086 | r = − 0.065 | r = − 0.204 | r = 0.067 | r = 0.159 | r = − 0.457 | r = − 0.114 | r = − 0.168 | r = − 0.521 | r = − 0.135 | r = 0.082 | r = 0.117 | N/A |
p = 0.224 | p = 0.660 | p = 0.738 | p = 0.290 | p = 0.730 | p = 0.409 | p = 0.013 | p = 0.557 | p = 0.385 | p = 0.004 | p = 0.484 | p = 0.672 | p = 0.547 | ||
miR-374b-5p | r = 0.177 | r = − 0.083 | r = 0.141 | r = 0.046 | r = − 0.013 | r = 0.151 | r = 0.333 | r = − 0.036 | r = 0.088 | r = − 0.023 | r = − 0.401 | r = − 0.407 | r = − 0.138 | N/A |
p = 0.358 | p = 0.669 | p = 0.466 | p = 0.812 | p = 0.948 | p = 0.436 | p = 0.078 | p = 0.854 | p = 0.648 | p = 0.904 | p = 0.031 | p = 0.028 | p = 0.475 | ||
miR-4433a-5p | r = 0.331 | r = 0.283 | r = 0.015 | r = − 0.05 | r = − 0.255 | r = 0.123 | r = − 0.126 | r = − 0.113 | r = − 0.030 | r = − 0.345 | r = − 0.329 | r = − 0.436 | r =− 0.090 | N/A |
p = 0.08 | p = 0.137 | p = 0.940 | p = 0.797 | p = 0.182 | p = 0.525 | p = 0.514 | p = 0.559 | p = 0.878 | p = 0.067 | p = 0.082 | p = 0.018 | p = 0.641 | ||
FM miRNA expression | ||||||||||||||
miR-150-5p | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | r = 0.33 |
p = 0.04 | ||||||||||||||
