Figure 2 | Scientific Reports

Figure 2

From: Blood unconjugated bilirubin and tacrolimus are negative predictors of specific cellular immunity in kidney transplant recipients after SAR-CoV-2 inactivated vaccination

Figure 2

T cell responses to pooled peptides from SARS-CoV-2 spike or nucleocapsid protein (NP) in kidney transplant recipients (KTR) and healthy participants (HPs) at 20 ± 5 days (KTRs1 and HPs1) and 45 ± 10 days (KTRs2 and HPs2) after the second dose of SARS-CoV-2 inactivated vaccine compared with KTRs or HPs without vaccination (KTRs0 and HPs0). (A) T cell responses targeted against SARS-CoV-2 spike in KTRs and HPs without vaccination, or at 20 ± 5 days and 45 ± 10 days after the second dose of inactivated vaccine. (B) The kinetic of spike specific T cells frequency in paired samples from KTRs and HPs at 20 ± 5 days (KTRs1 and HPs1) and 45 ± 10 days after the second dose of inactivated vaccine. (C) T cell responses targeted against SARS-CoV-2 NP in KTRs and HPs without vaccination or at 20 ± 5 days and 45 ± 10 days after the second dose of inactivated vaccine. (D) The kinetic of NP-specific T cell frequency in paired samples from KTRs and HPs at 20 ± 5 days (KTRs1 and HPs1) and 45 ± 10 days after the second dose of inactivated vaccine. The dotted line represents the cut-off value, which was calculated using mean + 3 standard deviations (SD) spike or NP-specific T cell frequency of HPs and KTRs without vaccination and COVID-19 history.

Back to article page