Figure 4

In vivo mouse xenograft models. Xenograft tumor growth over time per treatment condition (a), with box plots representing the relative tumor volume at end points (b). Evolution of mouse body weight over time (c) and at end points (d) were plotted. Each group consisted of 8 mice. Statistical significance was determined using Student’s t tests. *p < 0.05, **p < 0.01, ***p < 0.001.