Figure 4
From: Hypoxia-induced transcriptional differences in African and Asian versus European diabetic cybrids
Tight junction protein levels are similarly changed in hypoxia for European and [Afr + Asi], DM and Non-DM cybrids. Tight junction proteins in our cybrids cultured 48 h ± 2% O2 was measured using a western blot assay for (A) occludin, (B) the 205 kDa ZO-1α-minus isoform, and (C) the 225 kDa ZO-1α-plus isoform. For both groups of cybrids, data were normalized to protein levels in cybrids cultured in room air (red dotted line, value = 1). Afr + Asi = African + Asian; Euro = European; DM = Diabetic.
