Table 1 The hub targets of RD in BC treatment and the topological parameters.

From: The inhibitory effect and mechanism of Resina Draconis on the proliferation of MCF-7 breast cancer cells: a network pharmacology-based analysis

Number

Gene name

Protein name

Degree

1

AKT1

RAC-alpha serine/threonine-protein kinase

94

2

ESR1

Estrogen receptor 1

88

3

EGFR

Epidermal growth factor receptor

87

4

SRC

Proto-oncogene tyrosine-protein kinase Src

82

5

CASP3

Caspase-3

80

6

HSP90AA1

Heat shock protein 90 alpha family class A member 1

79

7

IGF1

Insulin-like growth factor 1

59

8

MDM2

MDM2 proto-oncogene

56

9

RHOA

Ras homolog family member A

55

10

MAPK1

Matrix metalloproteinase-1

55