Figure 3 | Scientific Reports

Figure 3

From: Environmental effects on brain functional networks in a juvenile twin population

Figure 3

ROI sorting based on link-level effects. A-C. Bar plots representing in light blue the number of functional connections influenced by epistasis (A), ADE factors (B), and ACE factors (C) in descending order in the 20 top ranking ROIs. Network links with significant correlation differences (p < 0.05) extracted from Fisher’s Z statistics between MZ and DZ pairs are highlighted in dark blue in panels (A, B). (DE) Functional connections suitable for ADE model weighted for their genetic (D) and environmental (E) contributions. In D, links with “broad-sense” heritability > 50% are highlighted in red. In E, links with unique environmental effects (E) > 50% are highlighted in cyan. F-G. Functional connections suitable for ACE model weighted for their genetic (F) and environmental (G) contributions. In G, links with “narrow-sense” heritability > 50% are highlighted in red. In G, links with common environmental effects (C) > 50% are highlighted in magenta. Panels were created with Matlab R2019b software (http://www.mathworks.com), assembled with Microsoft Power Point software (https://www.microsoft.com/it-it/microsoft-365/powerpoint) and exported using GIMP v.2–10 (https://www.gimp.org/).

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