Table 1 Demographics and asthma history of the participants by cluster.

From: Cluster analysis of plasma cytokines identifies two unique endotypes of children with asthma in the pediatric intensive care unit

Characteristic, n (%)

Cluster 1

n = 41

Cluster 2

n = 28

p-value

Age, yr, median (Q1, Q3)

11.0 [9.0,14.0]

9.5 [7.8,14.0]

0.495

Sex: female/male

15 (37)/26 (64)

13 (46)/15 (54)

0.570

BMI percentile, mean (SD)a

59 (35)

84 (23)

0.002

Self-identified race

 Black

34 (83)

25 (89)

0.861

 White

3 (7.3)

1 (3.3)

 American Indian

1 (2.4)

0 (0)

 Multi-racial or other

1 (2.4)

1 (3.6)

Self-identified ethnicity

1 (1.4)

1 (3.6)

0.393

Insurance

 Private

7 (17.5)

7 (25)

0.601

 Self-pay

1 (2.5)

0 (0)

 Government/Medicaid

31 (77.5)

21 (75)

 Military/Tricare

1 (2.5)

0 (0)

History of asthma prior to PICUb,c

35 (87.5)

25 (89)

> 0.9

Asthma Control Test, mean (SD)d

16 (6.2)

16 (4.2)

0.520

Home asthma medicationse

 None

5 (12)

4 (14)

> 0.9

 Albuterol or Xopenex

26 (63)

18 (64)

> 0.9

 Montelukast

12 (29)

14 (50)

0.136

 ICS

13 (32)

10 (36)

> 0.9

 ICS + LABA

10 (24)

9 (32)

0.665

 Omalizumab

1 (2.4)

2 (7.1)

0.562

 Daily oral corticosteroids

2 (2.9)

2 (7.1)

0.161

Daily use of β-agonist (at least 5/7 days)f

12 (34)

13 (52)

0.268

In past year, asthma resulted in:e,f

 Emergency/urgent care visits

17 (49)

19 (76)

0.061

 Hospitalized in PICU

4 (11)

7(28)

0.176

In lifetime, asthma resulted in:e,f

 Hospitalized in PICU

14 (40)

12 (48)

0.725

 Intubated for asthma

4 (11)

2 (8.0)

> 0.9

Medical historye

 Allergic rhinitis

9 (22)

8 (29)

0.732

 Eczema

22 (54)

18 (64)

0.529

 Sinusitis

1 (2.4)

0 (0)

> 0.9

Family asthma historye

 No one else has asthma

11 (27)

5 (18)

0.564

 Father

10 (24)

10 (36)

0.455

 Mother

13 (32)

10 (36)

0.931

 Sibling

10 (24)

6 (21)

> 0.9

Indoor exposurese

 None

14 (34)

5 (18)

0.225

 Tobacco smoke

15 (37)

8 (29)

0.665

 Pets

14 (34)

10 (36)

> 0.9

  1. aTen missing in Cluster 1, 2 in Cluster 2, bPediatric intensive care unit; cOne Missing in Cluster 1; d7 missing in Cluster 1, 6 in Cluster 2; eMore than one condition can be selected, and frequency total may add up to more than 100%; fSix missing in Cluster 1, 3 in Cluster 2.