Table 2 Subgroup analysis of serum HMGB1 levels of different febrile seizure types, seizure types, seizure duration, and family history of seizures.
Types | No. studies | SMD (95% CI) | Heterogeneity | Effect model | P value |
|---|---|---|---|---|---|
Types of FS | |||||
Complex vs. simple | 4 | 1.08 (0.67, 1.48) | 76.5% | Random | <0.001 |
Duration of FS | |||||
> 15 min vs. ≤ 15 min | 2 | 0.97 (0.68, 1.26) | 0% | Fixed | <0.001 |
Family history(FH) | |||||
With FH vs. no FH | 2 | 0.20 (− 0.20, 0.43) | 47.2% | Fixed | >0.05 |
Conversion to epilepsy | |||||
Yes vs. No | 2 | 0.56 (0.34, 0.79) | 45.9 | Fixed | <0.001 |
