Figure 2
(A) Estimated effect of current uric acid value on the hazard of kidney failure in all patients (n = 2344 including 382 KRT, Model 1 in Table 3). (B) Estimated effect of baseline uric acid value on the hazard of kidney failure in all patients (n = 2344, Model 3 in Table 3). Results from cause-specific Cox models using a spline function for uric acid, adjusted for age, sex, primary kidney disease, hypertension, diabetes, cardiovascular disease, dyslipidemia, body mass index, albuminuria, medication adherence, use of renin-angiotensin system inhibitors and urate lowering therapy, all at baseline. The reference value of uric acid for the HR indicated in the y-axis was arbitrarily chosen at 5 mg/dl, which corresponds to the midpoint of the normal range of uric acid (uric acid in mg/dl to µmol/l: × 59.48). CKD-REIN cohort, France, 2013–2018.
