Table 1 Various cases of acute phenoptosis prevented by mitochondria-targeted antioxidants.
From: Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks
No. | Inducers of acute phenoptosis | Antioxidant | References |
|---|---|---|---|
1. | LPS injection | SkQ1 | This article |
2. | Intravenous administration of mitochondria (mouse) | SkQ1 | This article |
3. | Cold stress at − 20 °C for 60 or 90 min (mouse) | SkQ1 | This article |
4. | Intravenous administration of C12TPP (34 μmol/kg body weight, mouse) | SkQ1 | This article |
5. | Intravenous administration of mitochondria + C12TPP (1.5 μmol/kg daily, 5 days, mouse) | SkQ1 | This article |
6. | Cold stress (60 min) + C12TPP (1.5 μmol/kg daily, 5 days, mouse) | SkQ1 | This article |
7. | Short-term ischemia of single-kidney animal (rat) | SkQ1, SkQR1 | |
8. | Short-term ischemia of single-kidney + injection of mitochondria (rat) | SkQ1 | Plotnikov et al.34 |
9. | LPS injection (newborn rat) | SkQR1 | Plotnikov et al.30 |
10. | Influenza A virus infection (mouse) | MitoTEMPO | To et al. (2020) 40 |
11. | Inflammatory cytokine TNF-a (mouse) | SkQ1 | Zakharova et al.35 |
12. | Autoimmune arthritis (rat) | SkQ1 | Andreev-Andrievskiy et al.37 |
