Table 1 Baseline characteristics of the study population.
From: High fibrinogen levels are associated with poor survival in patients with liposarcoma
Number (n) | % | |
|---|---|---|
Sex | ||
Male | 90 | 57 |
Female | 68 | 43 |
Tumor site | ||
Extremities | 137 | 86.7 |
Trunk | 12 | 7.6 |
Other | 9 | 5.7 |
Depth | ||
Epifascial | 19 | 12.0 |
Subfascial | 132 | 83.5 |
Not known | 7 | 4.4 |
Histology | ||
Highly differentiated | 44 | 27.8 |
Myxoid | 77 | 48.7 |
Dedifferentiated | 11 | 7.0 |
Pleomorph | 13 | 8.2 |
NOS | 13 | 8.2 |
Grading | ||
G1 | 55 | 34.8 |
G2 | 60 | 38.0 |
G3 | 43 | 27.2 |
Resection margins | ||
Wide | 61 | 38.6 |
Focal marginal | 43 | 27.2 |
Marginal | 27 | 17.1 |
Focal intralesional | 15 | 9.5 |
Intralesional | 5 | 3.2 |
Not known | 7 | 4.4 |
Local recurrence | 14 | 8.9 |
Metastasis | 18 | 11. 4 |
Tumor stage (AJCC) | ||
Stage IA | 2 | 2.5 |
Stage IB | 24 | 1.3 |
Stage II | 6 | 15.2 |
Stage IIIA | 31 | 19.6 |
Stage IIIB | 89 | 56.3 |
Stage IV | 2 | 1.3 |
Not known | 4 | 2.5 |
Tumor size | ||
≤ 2 cm | 1 | 0.6 |
> 2 ≤ 5 cm | 5 | 3.1 |
> 5 cm | 134 | 84.8 |
Not known | 18 | 11.4 |
Adjuvant therapy | ||
None | 44 | 27.8 |
Chemotherapy only | 2 | 1.3 |
Radiation only | 80 | 50.6 |
Both | 26 | 16.5 |
Neoadjuvant radiation | 11 | 6.69 |
Not known | 6 | 3.8 |
Age at baseline (years) | Mean | Range |
66.4 | 7–99 | |
Laboratory parameters | Median | Range |
Fibrinogen (mg/dL) | 353.0 | 132.0–956.0 |
C-reactive protein (mg/dL) | 1.16 | 0.03–21.0 |
Haemoglobin (g/dL) | 10.1 | 3.0–21.2 |
Alkalic phosphatase (U/L) | 72.5 | 32.0–238.0 |
NLR | 7.4 | 0.1–27.8 |
