Table 2 Relationship of four inflammatory cytokine signals by skin blotting method with IFSAT scores, severe facial skin problems, forehead erythema, forehead papules, and forehead dryness (n = 96).
Total (n = 96) | IFSAT† scores (n = 96) | Severe facial skin problems‡ (n = 55, 57.3%) | Forehead erythema (n = 16, 16.7%) | Forehead papules (n = 46, 47.9%) | Forehead dryness (n = 7, 7.3%) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | (%) | ρ | p-value | n | (%) | p-value | n | (%) | p-value | n | (%) | p-value | n | (%) | p-value | |
IL-4 signal | − 0.164 | 0.111|| | 0.222¶ | 0.355¶ | 0.629¶ | 0.465†† | ||||||||||
Positive | 40 | (41.7) | 20 | (50.0) | 5 | (12.5) | 18 | (45.0) | 2 | (5.0) | ||||||
Negative | 56 | (58.3) | 35 | (62.5) | 11 | (19.6) | 28 | (50.0) | 5 | (8.9) | ||||||
IL-6 signal | 0.046 | 0.660|| | 0.879¶ | 0.467†† | 0.635¶ | 0.292†† | ||||||||||
Positive | 25 | (26.0) | 14 | (56.0) | 3 | (12.0) | 13 | (52.0) | 3 | (12.0) | ||||||
Negative | 71 | (74.0) | 41 | (57.7) | 13 | (18.3) | 33 | (46.5) | 4 | (5.6) | ||||||
IL-8 signal | 0.279 | 0.006|| | 0.006¶ | 0.715¶ | 0.043¶ | 0.612†† | ||||||||||
Positive | 46 | (47.9) | 33 | (71.7) | 7 | (15.2) | 27 | (58.7) | 4 | (8.7) | ||||||
Negative | 50 | (52.1) | 22 | (44.0) | 9 | (18.0) | 19 | (38.0) | 3 | (6.0) | ||||||
IL-17 signal | − 0.049 | 0.639|| | 0.664¶ | 0.422¶ | 0.524¶ | 0.971†† | ||||||||||
Positive | 68 | (70.8) | 38 | (55.9) | 10 | (14.7) | 34 | (50.0) | 5 | (7.4) | ||||||
Negative | 28 | (29.2) | 17 | (60.7) | 6 | (21.4) | 12 | (42.9) | 2 | (7.1) | ||||||
