Table 2 Pre-existing conditions in selected populations.

From: Physiologic dead space is independently associated with mortality and discharge of mechanically ventilated patients with COVID-19 ARDS: a retrospective study

 

Starting population (n = 1567)

MV\(^{\dag }\) (n = 715)

No MV\(^{\ddag }\) (n = 137)

Final population (n = 401)

Dead (n = 150)

Discharged (n = 163)

Censored (n = 88)

None

239 (15.3)

107 (15.0)

29 (21.2)

63 (15.7)

14 (9.3)

33 (20.2)

16 (18.2)

Hypertension

905 (57.8)

429 (60)

73 (53.3)

236 (58.9)

104 (69.3)

81 (49.7)

51 (58.0)

Obesity

477 (30.4)

203 (28.4)

32 (23.4)

126 (31.4)

46 (30.7)

55 (33.7)

25 (28.4)

Type II DM, not on insulin

260 (16.6)

106 (14.8)

19 (13.9)

58 (14.5)

24 (16.0)

27 (16.6)

7 (8.0)

Type II DM, on insulin

117 (7.5)

51 (7.1)

6 (4.4)

25 (6.2)

10 (6.7)

5 (3.1)

10 (11.4)

Type I DM

11 (0.7)

2 (0.3)

2 (1.5)

1 (0.2)

0 (0)

1 (0.6)

0 (0)

COPD

133 (8.5)

53 (7.4)

28 (8.9)

25 (6.2)

7 (4.7)

13 (8.0)

5 (5.7)

COPD, moderate

114 (7.3)

48 (6.7)

9 (6.6)

23 (5.7)

6 (4.0)

12 (7.4)

5 (5.7)

COPD, severe

19 (1.2)

5 (0.7)

3 (2.2)

2 (0.5)

1 (0.7)

1 (0.6)

0 (0)

Asthma

65 (4.1)

26 (3.6)

3 (2.2)

14 (3.5)

5 (3.3)

7 (4.3)

0 (0)

Restrictive lung disease

6 (0.4)

3 (0.4)

0 (0)

2 (0.5)

0 (0)

2 (1.2)

0 (0)

Myocardial infarction

131 (8.4)

65 (9.1)

13 (9.5)

31 (7.7)

16 (10.7)

12 (7.4)

3 (3.4)

Arrhythmia

106 (6.8)

38 (5.3)

10 (7.3)

20 (5.0)

11 (7.3)

6 (3.7)

3 (3.4)

CHF (NYHA class 2 or 3)

40 (2.6)

13 (1.8)

6 (4.4)

4 (1.0)

2 (1.3)

1 (0.6)

1 (1.1)

Cancer, not metastatic

54 (3.4)

25 (3.5)

2 (1.5)

13 (3.2)

6 (4.0)

7 (4.3)

0 (0)

Hematological disorders

18 (1.1)

9 (1.3)

0 (0)

5 (1.2)

2 (1.3)

1 (0.6)

2 (2.3)

Autoimmune diseases

31 (2.0)

12 (1.7)

5 (3.6)

8 (2.0)

4 (2.7)

3 (1.8)

1 (1.1)

CKD, moderate or severe

80 (5.1)

33 (4.6)

8 (5.8)

15 (3.7)

6 (4.0)

8 (4.9)

1 (1.1)

CKD, end-stage

7 (0.4)

1 (0.1)

2 (1.5)

1 (0.2)

1 (0.7)

0 (0)

0 (0)

Cerebrovascular disease

54 (3.4)

26 (3.6)

7 (5.1)

13 (3.2)

7 (4.7)

4 (2.5)

2 (2.3)

Hemiplegia or paraplegia

13 (0.8)

8 (1.1)

2 (1.5)

5 (1.2)

3 (2.0)

1 (0.6)

1 (1.1)

Neuromuscular disease

11 (0.7)

4 (0.6)

3 (2.2)

0 (0)

0 (0)

0 (0)

0 (0)

  1. Data are number (%). \(^{\dag }\)MV indicates patients who received invasive mechanical ventilation (MV), via endotracheal intubation or tracheostomy, during their stay in the Intensive Care Unit. \(^{\ddag }\)No MV indicates patients who never received invasive mechanical ventilation during their stay. CHF chronic heart failure, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease, DM diabetes mellitus, NYHA New York functional classification for heart failure.
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