Table 3 Genotypes and allelic frequencies of ACE I/D and ACE G2350A genes in diabetic Patient and control groups.
Genotypes/alleles | Diabetic patients group (n = 108) | Control group (n = 85) | χ2 | P value |
---|---|---|---|---|
ACE I/D | ||||
Genotype (n) | ||||
II | 11 (10.2%) | 7 (8.2%) | 6.03 | 0.049* |
ID | 60 (55.6%) | 34 (40%) | ||
DD | 37 (34.2%) | 44 (51.8%) | ||
Allele (2n) | ||||
D | 134 | 122 | ||
I | 82 | 48 | ||
ACE (G2350A) | ||||
Genotype (n) | ||||
GG | 33 (30.6%) | 47 (55.3%) | 14.8 | 0.001** |
GA | 47 (43.5%) | 30 (35.3%) | ||
AA | 28 (25.9%) | 8 (9.4%) | ||
Allele (2n) | ||||
G | 113 (52.3%) | 124 (72.9%) | ||
A | 103 (47.7%) | 46 (27.1%) |