Table 4 Levels of studied biochemical parameters in different ACE2 G2350A genotypes in diabetic patient and control groups.

From: Diagnostic efficacy of cystatin-c in association with different ACE genes predicting renal insufficiency in T2DM

 

GG

GA

AA

Diabetic patient (n = 32)

Control (n = 43)

Diabetic patient (n = 44)

Control (n = 29)

Diabetic patient (n = 26)

Control (n = 8)

Serum glucose (mg/dL)

174.44 ± 76.10

84.54 ± 17.28

160.80 ± 87.0

92.87 ± 16.71

140.88 ± 57.43

97.13 ± 20.86

p value

0.001**

0.001**

0.048*

HbA1C (%)

7.05 ± 1.02

4.49 ± 0.67

8.2 ± 7.90

4.72 ± 0.64

6.72 ± 1.33

5.39 ± 0.56

p value

0.001**

0.001**

0.009**

Serum creatinine (mg/dL)

0.88 ± 0.20

0.83 ± 0.12

1.05 ± 0.65

0.83 ± .016

1.11 ± 1.0

0.8 ± 0.09

p value

0.13

0.18

0.37

Serum cyst-c (µg/L)

703.88 ± 382.24

527.28 ± 217.83

787.45 ± 635.04

525.90 ± 187.37

737.54 ± 729.84

521.63 ± 163.10

p value

0.014*

0.069

0.47

Urinary HO-1 (ng/mg creat)

16.35 ± 9.63

10.66 ± 10.20

14.36 ± 12.58

13.17 ± 7.41

21.91 ± 11.63

13.0 ± 12.0

p value

0.016*

0.57

0.017*

eGFR(mL/min/1.73m2)

111.5 ± 28.78

121.14 ± 24.06

102.28 ± 37.81

125.96 ± 35.99

105.85 ± 46.21

117.0 ± 26.42

p value

0.16

0.014*

0.4

  1. **High significant p < 0.001, *significant at p < 0.05.
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