Figure 1

Central figure. A swine model with elevated cholesterol levels was used in this study to simulate the progression of atherosclerotic disease. Various degrees of hemodynamic disturbances were induced in order to accelerate the progression of atherosclerosis and to ensure that it is known where the plaques originate so that it can be monitored. The hemodynamic and stiffness markers were calculated using Pulse Wave and Vector Flow Imaging. The key finding was that a greater ligation appeared to reduce wall shear stress more drastically. This distinct observed hemodynamic disturbance seemed to have resulted in a distinct estimated progression of compliance and distinct lesions.