Figure 8 | Scientific Reports

Figure 8

From: 5-methyladenosine regulators play a crucial role in development of chronic hypersensitivity pneumonitis and idiopathic pulmonary fibrosis

Figure 8

Analyses of immune checkpoints, small molecule drug therapy, GO, as well as KEGG Pathway in two m5Cclusters. (A) The boxplot of immune checkpoints in the two m5C patterns. *p < 0.05, **p < 0.01, and ***p < 0.001. (B) The expression of PDCD1 (PD-1) in the two m5C patterns. (C) The expression of CD274 (PD-L1) in the two m5C patterns. Two-dimensional molecular structure (D) and three-dimensional molecular structure (E) of ruxolitinib. The GO (F) and KEGG (G) enrichment analysis for the m5C-related differentially expressed genes (DEGs).

Back to article page