Figure 5

The DARs between H9c2 WT and Nono-KO cells. (A) Signal intensity plot representing changes in ATAC-seq signal at TSS regions following knockout of Nono in H9c2 cells. The enriched regions were extended ± 5 kb from their midpoint. (B) Scatter plot showing DARs between H9c2 WT and Nono-KO cells. (C) Heatmap analysis showing read density of ATAC-seq peaks in H9c2 WT and Nono-KO cells. (D) Biological process analysis of genes associated with decreased DARs. Top 10 significantly enriched GO terms are shown. (E) KEGG pathway analysis of genes associated with decreased DARs. Top 10 significantly enriched GO terms are shown. (F) Motif analysis of genes associated with decreased (top) or increased (bottom) DARs.