Table 1 Clinical features of study participants.

From: Small RNA sequencing of circulating small extracellular vesicles microRNAs in patients with amyotrophic lateral sclerosis

 

Discovery set

Validation set

ALS (n = 12)

Control (n = 11)

ALS (n = 18)

Control (n = 15)

Sex (M:F)

5:7

5:6

11:7

9:6

Age (years)

59 (37–76)

58 (52–75)

60 (52–76)

67 (53–77)

Disease duration (months)

17 (9–31)

–

5.5 (3–10)

–

Onset region

 Bulbar

6 (50%)

–

8 (44.4%)

–

 Limb

6 (50%)

–

10 (55.5%)

–

ALSFRS-R*

30.5 (18–46)

–

39 (19–45)

–

Level of diagnostic certainty

 Definite

5

 

12

 

 Probable

4

 

4

 

 Probable laboratory-supported

3

 

2

 
  1. Data are expressed as median value (min–max).
  2. ALS amyotrophic lateral sclerosis, M male, F female, ALSFRS-R ALS functional rating scale-revised.
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