Table 1 The 40 top differentially expressed genes (DEGs) in non-polyp nasal epithelial mucosa from patients with CRSwNP versus polyp mucosa in the same patient.
RNA | baseMean | log2FoldChange | lfcSE | stat | p value | padj |
|---|---|---|---|---|---|---|
CCL18 | 335.54 | 6.28 | 0.78 | − 8.01 | 1.12 × 10−15 | 3.67 × 10−11 |
CLEC4G | 75.28 | 6.11 | 0.78 | − 7.80 | 6.06 × 10−15 | 9.93 × 10−11 |
SLC9A3 | 460.64 | 3.96 | 0.52 | − 7.57 | 3.83 × 10−14 | 4.04 × 10−10 |
CCL13 | 222.07 | 5.29 | 0.70 | − 7.53 | 4.94 × 10−14 | 4.04 × 10−10 |
SLC9A3-AS1 | 810.12 | 1.23 | 0.16 | − 7.50 | 6.23 × 10−14 | 4.09 × 10−10 |
OXTR | 385.95 | 3.55 | 0.48 | − 7.47 | 7.75 × 10−14 | 4.23 × 10−10 |
C1QB | 533.27 | 2.61 | 0.35 | − 7.39 | 1.46 × 10−13 | 6.82 × 10−10 |
CDH26 | 1632.59 | 3.00 | 0.41 | − 7.37 | 1.77 × 10−13 | 7.23 × 10−10 |
F13A1 | 2594.99 | 3.21 | 0.45 | − 7.13 | 9.73 × 10−13 | 3.33 × 10−09 |
MARCO | 186.31 | 5.52 | 0.77 | − 7.13 | 1.02 × 10−12 | 3.33 × 10−09 |
CFI | 786.72 | 1.71 | 0.25 | − 6.92 | 4.58 × 10−12 | 1.37 × 10−08 |
PRH2 | 220.91 | − 5.71 | 0.83 | 6.87 | 6.58 × 10−12 | 1.80 × 10−08 |
RHAG | 24.29 | − 5.16 | 0.75 | 6.85 | 7.36 × 10−12 | 1.85 × 10−08 |
HES4 | 103.20 | 1.04 | 0.15 | − 6.82 | 8.80 × 10−12 | 2.06 × 10−08 |
SLC37A2 | 1936.03 | − 2.31 | 0.34 | 6.81 | 1.00 × 10−11 | 2.19 × 10−08 |
CLC | 251.95 | 5.31 | 0.78 | − 6.76 | 1.39 × 10−11 | 2.84 × 10−08 |
ANAPC5 | 3935.01 | − 0.43 | 0.06 | 6.75 | 1.47 × 10−11 | 2.84 × 10−08 |
CEBPE | 23.46 | 4.79 | 0.72 | − 6.70 | 2.12 × 10−11 | 3.87 × 10−08 |
GPAM | 529.09 | − 0.46 | 0.07 | 6.64 | 3.23 × 10−11 | 5.57 × 10−08 |
LACRT | 256.48 | − 4.67 | 0.71 | 6.61 | 3.73 × 10−11 | 6.12 × 10−08 |
DOK1 | 171.50 | 1.37 | 0.21 | − 6.56 | 5.51 × 10−11 | 8.60 × 10−08 |
PKDCC | 1217.18 | − 2.93 | 0.45 | 6.52 | 7.15 × 10−11 | 1.06 × 10−07 |
MS4A4A | 223.73 | 2.56 | 0.39 | − 6.51 | 7.61 × 10−11 | 1.08 × 10−07 |
KCTD17 | 80.18 | 1.15 | 0.18 | − 6.49 | 8.58 × 10−11 | 1.17 × 10−07 |
ST6GALNAC2 | 161.85 | 0.99 | 0.15 | − 6.45 | 1.10 × 10−10 | 1.44 × 10−07 |
HOXB-AS1 | 25.15 | 2.09 | 0.32 | − 6.45 | 1.15 × 10−10 | 1.44 × 10−07 |
SSBP4 | 441.60 | 0.98 | 0.15 | − 6.43 | 1.25 × 10−10 | 1.51 × 10−07 |
CEP72 | 214.53 | 1.28 | 0.20 | − 6.38 | 1.72 × 10−10 | 2.01 × 10−07 |
HK3 | 147.80 | 3.20 | 0.50 | − 6.37 | 1.85 × 10−10 | 2.10 × 10−07 |
PAFAH1B3 | 89.57 | 0.69 | 0.11 | − 6.34 | 2.32 × 10−10 | 2.48 × 10−07 |
ADAP1 | 46.78 | 1.29 | 0.20 | − 6.34 | 2.35 × 10−10 | 2.48 × 10−07 |
SYT17 | 148.54 | 1.47 | 0.23 | − 6.31 | 2.84 × 10−10 | 2.80 × 10−07 |
GABRP | 2266.10 | 2.16 | 0.34 | − 6.31 | 2.88 × 10−10 | 2.80 × 10−07 |
SIGLEC8 | 39.31 | 3.00 | 0.48 | − 6.30 | 2.90 × 10−10 | 2.80 × 10−07 |
SUCNR1 | 68.04 | 3.64 | 0.58 | − 6.30 | 3.05 × 10−10 | 2.86 × 10−07 |
C20orf197 | 29.59 | 1.88 | 0.30 | − 6.29 | 3.21 × 10−10 | 2.92 × 10−07 |
DNAJC25 | 226.50 | − 0.48 | 0.08 | 6.28 | 3.46 × 10−10 | 3.07 × 10−07 |
SCGB2A2 | 369.54 | − 4.00 | 0.64 | 6.26 | 3.76 × 10−10 | 3.23 × 10−07 |
PDLIM4 | 296.85 | 0.78 | 0.12 | − 6.26 | 3.91 × 10−10 | 3.23 × 10−07 |
FOLR2 | 139.85 | 2.48 | 0.39 | 6.25 | 3.94 × 10−10 | 3.23 × 10−07 |
