Table 3 The 40 top differentially expressed genes (DEGs) in non-polyp nasal epithelial mucosa from patients with CRSwNP versus mucosal tissue from controls.
RNA | baseMean | log2FoldChange | lfcSE | stat | p-value | padj |
|---|---|---|---|---|---|---|
PTP4A1 | 1777.09 | 0.97 | 0.14 | 6.78 | 1.21 × 10−11 | 3.41 × 10−07 |
FOSB | 646.71 | 4.65 | 0.70 | 6.64 | 3.19 × 10−11 | 3.95 × 10−07 |
GP2 | 1981.93 | 3.42 | 0.52 | 6.57 | 5.03 × 10−11 | 3.95 × 10−07 |
AC096642.1 | 61.77 | − 1.36 | 0.21 | − 6.55 | 5.60 × 10−11 | 3.95 × 10−07 |
TCEANC2 | 369.15 | − 0.65 | 0.10 | − 6.40 | 1.59 × 10−10 | 9.00 × 10−07 |
KLLN | 35.86 | − 0.90 | 0.14 | − 6.35 | 2.21 × 10−10 | 1.04 × 10−06 |
PTCD2 | 322.19 | − 0.43 | 0.07 | − 6.18 | 6.33 × 10−10 | 2.55 × 10−06 |
ELF2 | 1507.39 | 0.26 | 0.04 | 6.16 | 7.41 × 10−10 | 2.61 × 10−06 |
FOS | 2302.83 | 3.48 | 0.57 | 6.12 | 9.14 × 10−10 | 2.87 × 10−06 |
THNSL1 | 196.42 | − 0.83 | 0.14 | − 6.07 | 1.27 × 10−09 | 3.59 × 10−06 |
SRSF4 | 2023.33 | 0.40 | 0.07 | 6.05 | 1.49 × 10−09 | 3.82 × 10−06 |
LINC01578 | 1582.75 | 0.40 | 0.07 | 5.87 | 4.28 × 10−09 | 9.69 × 10−06 |
RPL5P18 | 12.89 | − 1.36 | 0.23 | − 5.87 | 4.46 × 10−09 | 9.69 × 10−06 |
PEX12 | 151.12 | − 0.55 | 0.09 | − 5.83 | 5.66 × 10−09 | 1.12 × 10−05 |
ZNF708 | 518.62 | 0.34 | 0.06 | 5.81 | 6.22 × 10−09 | 1.12 × 10−05 |
TRMO | 389.92 | 0.36 | 0.06 | 5.80 | 6.65 × 10−09 | 1.12 × 10−05 |
ADAM20P1 | 71.89 | − 0.90 | 0.15 | − 5.80 | 6.75 × 10−09 | 1.12 × 10−05 |
AVL9 | 1876.16 | 0.23 | 0.04 | 5.78 | 7.48 × 10−09 | 1.15 × 10−05 |
BACH1 | 1744.81 | 0.42 | 0.07 | 5.77 | 7.76 × 10−09 | 1.15 × 10−05 |
FBXO33 | 464.49 | 0.47 | 0.08 | 5.76 | 8.66 × 10−09 | 1.18 × 10−05 |
AC105285.1 | 50.92 | − 0.88 | 0.15 | − 5.75 | 8.81 × 10−09 | 1.18 × 10−05 |
TRMT1L | 658.27 | − 0.49 | 0.09 | − 5.70 | 1.17 × 10−08 | 1.50 × 10−05 |
SECISBP2 | 2027.42 | 0.29 | 0.05 | 5.67 | 1.44 × 10−08 | 1.77 × 10−05 |
DACT2 | 133.52 | 1.20 | 0.21 | 5.64 | 1.66 × 10−08 | 1.90 × 10−05 |
USP3 | 1582.27 | 0.33 | 0.06 | 5.64 | 1.68 × 10−08 | 1.90 × 10−05 |
HNRNPH1 | 10 575.10 | 0.30 | 0.05 | 5.62 | 1.93 × 10−08 | 1.98 × 10−05 |
ZNF311 | 80.44 | − 0.83 | 0.15 | − 5.61 | 1.97 × 10−08 | 1.98 × 10−05 |
KDM3A | 2057.25 | 0.46 | 0.08 | 5.61 | 2.00 × 10−08 | 1.98 × 10−05 |
ZNF292 | 3415.61 | 0.40 | 0.07 | 5.61 | 2.04 × 10−08 | 1.98 × 10−05 |
RINT1 | 517.18 | 0.26 | 0.05 | 5.60 | 2.11 × 10−08 | 1.98 × 10−05 |
MAP3K21 | 260.50 | 0.62 | 0.11 | 5.59 | 2.30 × 10−08 | 2.10 × 10−05 |
USP48 | 2054.50 | 0.32 | 0.06 | 5.55 | 2.84 × 10−08 | 2.51 × 10−05 |
TTC39C | 962.55 | 0.31 | 0.06 | 5.54 | 3.09 × 10−08 | 2.64 × 10−05 |
CCDC112 | 216.29 | 0.61 | 0.11 | 5.50 | 3.79 × 10−08 | 3.07 × 10−05 |
USP37 | 1073.22 | − 0.30 | 0.06 | − 5.49 | 3.93 × 10−08 | 3.07 × 10−05 |
RIC8B | 498.24 | − 0.34 | 0.06 | − 5.49 | 3.98 × 10−08 | 3.07 × 10−05 |
MOAP1 | 463.38 | 0.44 | 0.08 | 5.49 | 4.03 × 10−08 | 3.07 × 10−05 |
MCMDC2 | 44.72 | − 0.95 | 0.17 | − 5.47 | 4.47 × 10−08 | 3.32 × 10−05 |
CBR3-AS1 | 293.55 | 0.90 | 0.17 | 5.46 | 4.80 × 10−08 | 3.40 × 10−05 |
AC007485.2 | 78.67 | − 0.53 | 0.10 | − 5.46 | 4.81 × 10−08 | 3.40 × 10−05 |
