Figure 4

Infection with M. avium does not induce morphological alterations in granule neurons of the hippocampus. Dendritic morphology of granule neurons from the DG was analyzed in M. avium infected (4 wpi) and non-infected Balb/c, C57BL/6 and CD1 mice. The total length of the dendritic tree (A–C) and Sholl analysis of the number of intersections of dendrites at specific distances from the soma are displayed (D–F). Each bar represents the mean + SEM of the average length of 28–31 granule neurons per group, from 5 to 6 mice per group; the lines represent the average number of intersections of dendrite branches with consecutive 10 µm-spaced concentric spheres of the same neurons.