Table 3 Neuropsychological assessment scores stratified by age and sex.

From: Sex and age affect acute and persisting COVID-19 illness

 

Total (N = 72)

Younger adults (< 60 y.o.)

Older adults (60 + y.o.)

P value

Female (N = 38)

Male (N = 15)

Female (N = 10)

Male (N = 9)

Age

Sex

Age × Sex

TorCA or MOCA, obtained/max. score

0.9 (0.1)

0.9 (0.1)

0.9 (0.1)

0.9 (0.1)

0.8 (0.1)

.2

.09

.05

 

Total (N = 45)

Female (N = 21)

Male (N = 7)

Female (N = 8)

Male (N = 9)

Age

Sex

Age × Sex

TorCA domain scores, Mean (S.D.)

 Memory orientation

11.9 (0.4)

12.0 (0.2)

12.0 (0)

11.9 (0.4)

11.8 (0.7)

.2

.8

.5

  Normal

44 (98%)

21 (100%)

7 (100%)

8 (100%)

8 (89%)

NA

NA

NA

  Borderline/impaired

1 (2%)

0

0

0

1 (11%)

 Memory immediate recall

19.6 (4.4)

20.3 (5.4)

19.7 (1.8)

20.3 (3.5)

17.6 (3.8)

.4

.2

.4

  Normal

23 (51%)

10 (48%)

2 (29%)

6 (75%)

5 (56%)

.1

.2

1

  Borderline/impaired

22 (49%)

11 (52%)

5 (71%)

2 (25%)

4 (44%)

 Memory delayed recall

19.1 (4.1)

19.8 (4.2)

19.0 (5.9)

18.8 (2.9)

17.9 (3.3)

.4

.5

1

  Normal

35 (78%)

16 (76%)

5 (71%)

6 (75%)

8 (89%)

.5

.7

.5

  Borderline/impaired

10 (22%)

5 (24%)

2 (29%)

2 (25%)

1 (11%)

 Memory delayed recognition

20.0 (2.3)

20.1 (1.4)

21.4 (3.9)

19.1 (3.0)

19.7 (1.4)

.05

.2

.5

  Normal

27 (60%)

12 (57%)

3 (43%)

6 (75%)

6 (67%)

.2

.5

.9

  Borderline/impaired

18 (40%)

9 (43%)

4 (57%)

2 (25%)

3 (33%)

 Visuospatial function

30.2 (2.6)

30.0 (3.0)

30.9 (1.6)

30.5 (1.4)

29.8 (3.3)

.7

1

.4

  Normal

41 (91%)

18 (86%)

7 (100%)

8 (100%)

8 (89%)

NA

NA

NA

  Borderline/impaired

4 (9%)

3 (14%)

0

0

1 (11%)

 Working memory/attention/executive function

94.4 (16.4)

95.8 (13.2)

95.0 (14.5)

98.4 (16.0)

87.0 (24.3)

.6

.2

.3

  Normal

9 (20%)

4 (19%)

2 (29%)

2 (25%)

1 (11%)

.1

.2

1

  Borderline/impaired

36 (80%)

17 (81%)

5 (71%)

6 (75%)

8 (89%)

 Language

95.0 (14.1)

93.6 (11.8)

97.0 (9.1)

96.8 (12.3)

95.1 (23.1)

.8

1

.5

  Normal

41 (91%)

18 (86%)

7 (100%)

7 (87.5%)

9 (100%)

NA

NA

NA

  Borderline/impaired

4 (9%)

3 (14%)

0

1 (12.5%)

0

 TorCA total score

290.3 (22.3)

291.6 (24.3)

295.0 (22.6)

295.6 (21.3)

278.8 (16.3)

.5

.2

.1

  1. Data presented as Mean (S.D.). Patients admitted to ICU and/or with abnormal brain MRI findings are excluded. Linear and binary regressions adjusted for combined past medical history and symptom duration. All neuropsychological scores where z-scores were not computed were additionally adjusted for years of education. Significant values are in [bold].