Table 6 Baseline results using data preprocessed following the approach proposed by Carreiro et al.12 learned with 4 classifiers: Naive Bayes (NB), Support Vector Machine (SVM), Random Forests (RF) and XGB (eXtreme Gradient Boosting) to predict the Evolution for each of the target endpoints, C1, C2, and C3, within the considered time windows (90, 180 and 365 days), respectively.

From: Triclustering-based classification of longitudinal data for prognostic prediction: targeting relevant clinical endpoints in amyotrophic lateral sclerosis

 

AUC

Sensitivity

Specificity

C1—Need for NIV

 90 days

  NB

77.23 ± 3.55

62.84 ± 7.56

74.30 ± 1.53

  SVM

74.06 ± 4.34

71.41 ± 9.55

66.00 ± 3.43

  RF

74.97 ± 3.20

57.52 ± 7.85

76.34 ± 1.96

  XGB

77.59 ± 2.78

61.70 ± 7.57

77.17 ± 1.77

 180 days

  NB

76.23 ± 1.86

63.70 ± 4.41

74.87 ± 1.63

  SVM

75.35 ± 1.66

71.32 ± 3.65

66.99 ± 2.33

  RF

76.11 ± 1.69

61.08 ± 4.53

76.72 ± 1.88

  XGB

76.75 ± 1.70

61.83 ± 4.16

76.16 ± 1.79

 365 days

  NB

72.23 ± 1.43

55.96 ± 2.71

74.49 ± 2.34

  SVM

71.66 ± 1.49

67.50 ± 2.36

65.33 ± 2.52

  RF

78.34 ± 2.03

63.50 ± 3.57

78.11 ± 1.84

  XGB

75.60 ± 1.77

61.20 ± 3.00

75.68 ± 1.78

C2—need for an auxiliary communication device

 90 days

  NB

87.69 ± 2.82

81.93 ± 6.24

78.19 ± 1.90

  SVM

83.31 ± 4.46

75.28 ± 10.58

73.85 ± 3.06

  RF

85.71 ± 3.20

70.14 ± 9.34

81.80 ± 2.19

  XGB

86.44 ± 2.93

73.86 ± 7.64

80.87 ± 1.94

 180 days

  NB

88.68 ± 1.36

82.94 ± 4.64

78.74 ± 1.15

  SVM

89.81 ± 1.45

84.43 ± 4.25

79.76 ± 1.29

  RF

89.31 ± 1.03

78.56 ± 4.20

82.94 ± 1.40

  XGB

89.53 ± 1.03

81.34 ± 3.53

82.33 ± 1.38

 365 days

  NB

86.66 ± 1.83

78.93 ± 3.46

80.22 ± 1.21

  SVM

88.13 ± 1.67

81.82 ± 2.78

80.85 ± 1.26

  RF

88.28 ± 1.27

75.87 ± 3.94

83.47 ± 1.26

  XGB

88.18 ± 1.28

76.59 ± 3.56

82.88 ± 1.33

C3—need for PEG

 90 days

  NB

87.79 ± 2.64

82.33 ± 8.27

80.03 ± 1.77

  SVM

84.39 ± 4.70

83.00 ± 13.01

70.19 ± 4.14

  RF

86.28 ± 2.92

71.00 ± 12.05

83.91 ± 2.03

  XGB

88.32 ± 1.92

77.67 ± 8.41

82.98 ± 2.14

 180 days

  NB

88.24 ± 1.71

81.76 ± 5.44

79.09 ± 1.46

  SVM

90.30 ± 1.59

85.84 ± 4.83

79.80 ± 1.32

  RF

88.59 ± 1.55

75.92 ± 5.95

83.84 ± 1.39

  XGB

89.38 ± 1.56

81.04 ± 5.52

83.75 ± 1.27

 365 days

  NB

84.82 ± 1.62

76.08 ± 3.90

76.55 ± 1.45

  SVM

87.16 ± 1.67

80.21 ± 3.70

78.98 ± 1.48

  RF

86.76 ± 1.29

74.28 ± 3.06

82.62 ± 1.34

  XGB

86.74 ± 1.47

75.09 ± 3.92

81.76 ± 1.38