Table 2 Results of subgroup analysis based on different standards.
Group | Sensitivity (95% CI) | Specificity (95% CI) | I2 | PLR (95% CI) | NLR (95% CI) | DOR (95% CI) | AUROC (95% CI) | |
|---|---|---|---|---|---|---|---|---|
20 studies | 0.79 (0.72–0.84) | 0.70 (0.62–0.76) | 97 | 2.6 (2.1–3.3) | 0.31 (0.23–0.40) | 8 (6–13) | 0.81 (0.78–0.84) | |
Age | Mean age ≥ 65y (n = 9) | 0.76 (0.65–0.83) | 0.72 (0.61–0.81) | 0 | 2.7 (1.7–4.1) | 0.34 (0.22–0.54) | 8 (3–18) | 0.8 (0.77–0.83) |
Mean age < 65y (n = 10) | 0.81 (0.74–0.87) | 0.70 (0.58–0.79) | 97 | 2.7 (2.0–3.6) | 0.27 (0.20–0.36) | 10 (7–15) | 0.83 (0.80–0.86) | |
Criterion | All stage (n = 15) | 0.77 (0.69–0.84) | 0.69 (0.60–0.77) | 97 | 2.5 (1.9–3.2) | 0.33 (0.24–0.45) | 8 (5–12) | 0.8 (0.76–0.83) |
Stage 2–3 (n = 5) | 0.84 (0.73–0.91) | 0.72 (0.56–0.84) | 40 | 3.0 (1.8–5.0) | 0.23 (0.12–0.41) | 13 (5–37) | 0.86 (0.83–0.89) | |
Time of measurement | Within 12 h (n = 9) | 0.81 (0.73–0.86) | 0.62 (0.53–0.70) | 93 | 2.1 (1.7–2.6) | 0.32 (0.23–0.43) | 7 (4–10) | 0.78 (0.74–0.82) |
12-24 h (n = 4) | 0.81 (0.66–0.90) | 0.67 (0.54–0.78) | 0 | 2.4 (1.5–3.9) | 0.29 (0.14–0.60) | 8 (3–27) | 0.80 (0.76–0.83) | |
24-48 h (n = 7) | 0.74 (0.59–0.85) | 0.82 (0.73–0.88) | 38 | 4.1 (2.5–6.7) | 0.31 (0.18–0.54) | 13 (5–34) | 0.86 (0.82–0.88) | |
Clinical setting | Cardiac surgery (n = 10) | 0.73 (0.63–0.81) | 0.76 (0.68–0.83) | 68 | 3.1 (2.1–4.5) | 0.35 (0.24–0.51) | 9 (5–17) | 0.81 (0.77–0.84) |
ICU and ED (n = 7) | 0.83 (0.75–0.89) | 0.54 (0.48–0.61) | 88 | 1.8 (1.6–2.1) | 0.32 (0.22–0.46) | 6 (4–9) | 0.73 (0.69–0.77) | |
Others (n = 3) | 0.80 (0.71–0.87) | 0.79 (0.72–0.85) | 4.0 (3.0–5.4) | 0.24 (0.09–0.59) | 25 (6–110) | 0.9 (0.80–0.99) | ||
Cut-off value | = 0.3 (n = 11) | 0.79 (0.70–0.86) | 0.62 (0.53–0.70) | 96 | 2.1 (1.7–2.6) | 0.34 (0.23–0.49) | 6 (4–11) | 0.76 (0.72–0.80) |
≠ 0.3 (n = 10) | 0.78 (0.71–0.83) | 0.76 (0.66–0.84) | 81 | 3.3 (2.3–4.7) | 0.29 (0.22–0.38) | 11 (7–19) | 0.82 (0.79–0.86) |
