Table 2 Molecular sensors of mechanical pain for which no positive evidence was found that they also transmit thermal nociception, or for which negative evidence has been found with respect to an involvement in thermal nociception.
Gene symbol | Gene name | NCBI number | Gene name via NCBI | UNIPROT Id | Reference |
|---|---|---|---|---|---|
ASIC1 | Acid sensing ion channel subunit 1 | 41 | ASIC1 | A8K1U5 | |
ASIC2 | Acid sensing ion channel subunit 2 | 40 | ASIC2 | Q16515 | |
ASIC3 | Acid sensing ion channel subunit 3 | 9311 | ASIC3 | A0A090N7X8 | |
CACNA1C | Calcium voltage-gated channel subunit alpha1 C | 775 | CACNA1C | Q13936 | |
FXYD2 | FXYD domain containing ion transport regulator 2 | 486 | FXYD2 | P54710 | |
GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1 | 2902 | GRIN1 | Q05586 | |
HCN2 | Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 | 610 | HCN2 | Q9UL51 | |
KCNJ8 | Potassium inwardly rectifying channel subfamily J member 8 | 3764 | KCNJ8 | A0A024RAV6 | |
P2RY6 | Pyrimidinergic receptor P2RY6 | 5031 | P2RY6 | A0A024R5I9 | |
PIEZO1 | Piezo type mechanosensitive ion channel component 1 | 9780 | PIEZO1 | Q92508 | |
PIEZO2 | Piezo type mechanosensitive ion channel component 2 | 63,895 | PIEZO2 | Q9H5I5 | |
SCNN1A | Sodium channel epithelial 1 subunit alpha | 6337 | SCNN1A | P37088 | |
SLO1 | Potassium calcium-activated channel subfamily M alpha 1 | 3778 | KCNMA1 | Q12791 |
