Figure 6 | Scientific Reports

Figure 6

From: Metabolomics profiling distinctively identified end-stage renal disease patients from chronic kidney disease patients

Figure 6

(A) Main steps of branched chain amino acids (BCAA) catabolism. BCAT and BCKD stand for branched-chain amino acid transaminase and branched-chain keto acid dehydrogenase, respectively. (B) The kynurenine pathway of tryptophan metabolism. IDO indoleamine 2,3-dioxygenase, TDO tryptophan 2,3-dioxygenase, KAT kynurenine aminotransaminase, KMO kynurenine 3-monooxygenase, KYNU kynureninase, NAD+ Nicotinamide adenine dinucleotide. Red and blue arrows indicate increase and decrease in the level of the metabolite in ESRD compared to CKD, respectively.

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