Table 3 Univariate and multivariable analyses for liver fibrosis and cirrhosis.

From: TET3 as a non-invasive screening tool for the detection of fibrosis in patients with chronic liver disease

 

Fibrosis (n = 220)

Cirrhosis (n = 292)

Univariate Analysis

Multivariate Analysis

Univariate Analysis

Multivariate Analysis

OR (95% CI)

P Value

OR (95% CI)

P Value

OR (95% CI)

P Value

OR (95% CI)

P Value

Age (yr)

1.031(1.009–1.054)

0.007

1.018(0.983–1.054)

0.330

1.030(1.009–1.053)

0.006

0.987(0.949–1.028)

0.534

Gender (n)

1.063(0.619–1.826)

0.825

 

NA

2.157(1.175–3.958)

0.013

2.396(0.965–5.951)

0.060

ALT (U/L)

0.996(0.992–1.000)

0.052

 

NA

1.000(0.998–1.003)

0.727

 

NA

AST (U/L)

0.999(0.993–1.004)

0.617

 

NA

1.006(1.002–1.010)

0.007

0.994(0.968–1.021)

0.682

PLT (× 109/L)

0.983(0.978–0.989)

 < 0.0001

0.993(0.985–1.002)

0.124

0.972(0.965–0.979)

 < 0.0001

0.985(0.975–0.996)

0.008

APRI score

1.312(0.947–1.818)

0.103

 

NA

2.120(1.604–2.802)

 < 0.0001

0.927(0.368–2.335)

0.872

FIB-4 index

2.373(1.625–3.465)

 < 0.0001

1.646(1.014–2.672)

0.044

1.772(1.494–2.102)

 < 0.0001

1.533(1.019–2.306)

0.040

TET3 (ng/mL)

1.007(1.004–1.009)

 < 0.0001

1.006(1.004–1.008)

 < 0.0001

1.002(1.002–1.003)

 < 0.0001

1.002(1.001–1.003)

 < 0.0001

  1. NA: not adopted.
Back to article page