Table 1 Patient demographics and haematological and biochemical variables.
From: Serum lipid mediator profiles in COVID-19 patients and lung disease severity: a pilot study
Control (n = 7) | Mild (n = 8) | Moderate (n = 8) | Severe (n = 8) | P -value | |
---|---|---|---|---|---|
Demographics | |||||
Age (years) | 45.0 (43.5–45.5) | 50.5 (40.8–78.5) | 79.0 (65.3–87.0) | 69.0 (60.3–82.3) | 0.015a 0.013b |
Gender | 0.606 | ||||
Male | 6 (85.7%) | 5 (62.5%) | 4 (50.0%) | 6 (75.0%) | |
Female | 1 (14.3%) | 3 (37.5%) | 4 (50.0%) | 2 (25.0%) | |
Blood determinations | |||||
ALT, μkat/l | 0.28 (0.21–0.56) | 0.40 (0.20–0.65) | 0.62 (0.53–1.11) | 0.082 | |
AST, μkat/l | 0.40 (0.34–0.56) | 0.58 (0.38–1.18) | 0.78 (0.63–1.01) | 0.057 | |
CRP, mg/l | 52.6 (8.9–104.3) | 69.8 (51.1–142.9) | 131.8 (48.5–201.0) | 0.531 | |
Chloride, mmol/l | 101.3 (98.4–102.5) | 103.1 (100.1–111.3) | 101.0 (96.1–102.7) | 0.267 | |
CK, μkat/l | 1.03 (0.70–1.42) | 3.23 (1.26–8.34) | 1.68 (0.86–1.95) | 0.224 | |
aPTT, s | 32.3 (30.1–33.7) | 31.8 (31.2–34.0) | 28.0 (26.6–29.9) | 0.021a 0.010c | |
Creatinine, μmol/l | 83.5 (67.9–98.4) | 83.1 (77.8–100.8) | 111.4 (77.8–192.9) | 0.383 | |
Basophils count, 109/l | 0.02 (0.01–0.03) | 0.01 (0.01–0.02) | 0.01 (0.01–0.04) | 0.315 | |
Eosinophils count, 109/l | 0.09 (0.01–0.13) | 0.00 (0.00–0.01) | 0.00 (0.00–0.01) | 0.034a 0.035b | |
Erythrocytes count, 1012/l | 4.3 (4.1–4.8) | 4.2 (3.8–5.3) | 4.1 (4.0–4.1) | 0.357 | |
Hematocrit, l/l | 0.40 (0.37–0.45) | 0.37 (0.36–0.46) | 0.36 (0.35–0.38) | 0.103 | |
Lymphocytes count, 109/l | 0.83 (0.52–1.18) | 0.74 (0.63–0.98) | 0.51 (0.44–0.61) | 0.229 | |
Platelets count, 109/l | 167.5 (141.8–217.8) | 177.0 (149.0–193.5) | 225.0 (144.3–254.3) | 0.481 | |
Potassium, mmol/l | 4.0 (3.8–4.1) | 3.9 (3.8–4.0) | 3.8 (3.3–4.5) | 0.918 | |
PT, s | 15.5 (13.2–17.8) | 13.8 (13.3–17.0) | 14.2 (13.5–15.5) | 0.822 | |
Sodium, mmol/l | 139.5 (137.0–141.0) | 141.5 (139.3–150.3) | 138.0 (134.0–140.0) | 0.172 | |
Cardiac troponin T, μg/l | 0.01 (0.01–0.02) | 0.01 (0.01–0.02) | 0.02 (0.01–0.04) | 0.528 | |
BUN, mmol/l | 8.7 (7.9–13.1) | 17.1 (14.3–18.7) | 24.8 (22.1–48.2) | 0.027a 0.049b |