Table 4 Results of a multivariate Cox proportional hazards model for the effect of gender on outcome events in patients with HFmrEF.

From: Sex differences in patients with heart failure and mildly reduced left ventricular ejection fraction

Outcome

Non-adjusted hazard ratio (95% CI)

P-value

Adjust I hazard ratio (95% CI)

P-value

Adjust II hazard ratio (95% CI)

P-value

Ninety day all-cause death

 Female

Reference

 Male

1.25 (0.74, 2.11)

0.406

1.38 (0.82, 2.34)

0.228

1.84 (1.02, 3.34)

0.045

One year all-cause death

 Female

Reference

 Male

0.99 (0.74, 1.33)

0.970

1.09 (0.81, 1.46)

0.586

1.33 (0.94, 1.89)

0.104

Ninety day CV events

 Female

Reference

 Male

0.98 (0.79, 1.21)

0.836

1.02 (0.83, 1.26)

0.861

1.09 (0.86, 1.39)

0.467

One year CV events

 Female

Reference

 Male

0.92 (0.80, 1.06)

0.269

0.95 (0.83, 1.10)

0.524

1.00 (0.85, 1.19)

0.966

  1. Adjust I model adjust for: age.
  2. Adjust II model adjust for: age; body mass index; current smoker; current drinker; hypertension; hyperlipidemia; diabetes mellitus; coronary heart disease; atrial fibrillation; previous stroke; chronic obstructive pulmonary disease; renal insufficiency; New York Heart Association; eGFR; NT-proBNP; heart rate; systolic blood pressure; myocardial infarction; percutaneous coronary intervention; estimated glomerular filtration rate.