Figure 1

Schematic display of the clinical trial. Study arm 1 was an open-label study in which all participants were treated with Q-GRFT (n = 3). This was followed by a randomized, blinded trial, in which study arms 2 and 3 were treated with Q-GRFT (n = 8) and placebo (n = 4), respectively. Abbreviations: Bx1, biopsy 1; Bx2, biopsy 2; PSRT, Protocol Safety Review Team.