Table 3 Univariate and Multivariate analysis for variables associated with severe lymphopenia.

From: Severe lymphopenia as a prognostic factor in rectal cancer patients receiving adjuvant chemoradiotherapy: a retrospective study

Clinical factors

Univariate analysis

Multivariable analysis

HR

95% CI

p

HR

95% CI

p

Age (≤ 60 vs > 60)

1.257

0.333–4.742

0.735

   

Sex (female vs male)

2.062

0.492–8.654

0.322

   

N status (N+ vs N−)

1.250

0.299–5.230

0.760

   

CEA (> 4.0 vs ≤ 4.0)

0.606

0.158–2.319

0.464

   

Pre-S TLCs (low vs high)

8.000

1.686–37.981

0.009

6.246

11.248–31.257

0.026

Pre-RT TLCs (low vs high)

4.469

1.054–18.938

0.042

3.025

0.624–14.662

0.169

  1. N lymph node, N+ lymph node positive, N− lymph node negative, CEA carcino-embryonic antigen, pre-S TLCs total lymphocyte counts before surgery, pre-RT TLCs total lymphocyte counts before concurrent chemoradiotherapy.