Figure 1 | Scientific Reports

Figure 1

From: Effects of rIL2/anti-IL2 antibody complex on chikungunya virus-induced chronic arthritis in a mouse model

Figure 1

CHIKV post-acute arthritis mouse model with IL2-based treatments. C57BL/6 adult mice were infected with CHIKV via footpad injection. Mice were confirmed positive for CHIKV at two days post-infection (dpi) and confirmed negative by 16 dpi. Recombinant IL2, anti-IL2 monoclonal antibody (mAb), or a rIL2/anti-IL2 mAb complex were administered via intraperitoneal injection once per day for three days, starting at 16 dpi. Mice were sacrificed at 19 dpi, and spleen, hind limbs, and blood were collected for future analysis. Tarsal joints were measured daily.

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