Figure 2

Spearman correlation of microbiome profiles and metabolomic profiles. Single microbial taxa correlated with clinically validated metabolomic data using Spearman’s rank sum non-parametric test. FDR P-values are displayed *P < 0.01. Rows and columns are hierarchically clustered (Euclidean distance). The R package ‘corrplot_0.90' (https://github.com/taiyun/corrplot) was used to compute the variance and the covariance or correlation. The packages ‘pheatmap_1.0.12’ (https://cran.r-project.org/web/packages/pheatmap/index.html) and the ‘cor.mtest' function of ‘corrplot_0.90’ were used to visualise the heatmap and calculate associated P values.