Table 5 Table describing definitions used to group individuals based on their swab (RT-PCR) or antibody test status and duration of symptoms, as logged in ZOE COVID Symptom Study app.

From: Metabolomic and gut microbiome profiles across the spectrum of community-based COVID and non-COVID disease

Group

For swab test

For antibody Test-If no appropriate swab available

AsymptomaticCOVID-19

Positive swab with no symptoms around test (14 days before to 7 days after inclusive), with logging at least every 7 days

Positive antibodies with no symptoms before test including in “past symptoms”, with logging at least every 7 days

Acute COVID-19 illness (ACI)

Positive swab test with swab taken up to 7 days prior, or 14 days after onset of symptoms

Positive antibody test, with symptomatic symptoms lasting 7 days or less, starting > 14 days before testing

Ongoing symptomatic COVID-19 (OSC28)

Positive swab, around onset of symptoms (as above). Symptoms lasting over 28 days up to 84 days

Positive antibody test, with symptoms lasting over 28 up to 84 days, starting > 14 days before testing

Post COVID-19 syndrome (PCS84)

Positive swab test with symptoms lasting ≥ 84 days

Positive antibody test, with symptoms lasting ≥ 84 days starting > 14 days before testing

Negative Non-COVID-19 illness 28–83 days (NC28)

Negative swab test in first 2 weeks of symptoms, and symptoms lasting 28 to 83 days inclusive. No other positive test during logging, including a negative antibody test at enrolment

Negative antibody test > 14 days after onset of symptoms, with symptoms lasting 28 to 83 days inclusive

Negative Non-COVID-19 illness ≥ 84 days (NC84)

Negative swab test in first 2 weeks of symptoms, and symptoms lasting ≥ 84-days. No other positive test during logging, including a negative antibody test at enrolment

Negative antibody test > 14 days after onset of symptoms, with symptoms lasting ≥ 84 days

  1. Intermediate groups show in S Table 1.