Table 1 Differentially regulated transcripts (identified by their accession numbers and gene names IDs) with the highest fold change (LogFC) from the comparison of cells incubated with EV of trypomastigotes of T. cruzi (CEV) to control cells (CC).

From: Extracellular vesicles of trypomastigotes of Trypanosoma cruzi induce changes in ubiquitin-related processes, cell-signaling pathways and apoptosis

Accession number

Gene ID

CC

CEV

LogFC

Prob

Biotype

Name

NR_122069

HOXA-AS2

18.83

0.50

5.23

0.98

lncRNA

HOXA cluster antisense RNA 2

XM_024451477

CCDC106

17.65

0.50

5.14

0.98

protein_coding

Coiled-coil domain containing 106 (CCDC106)

NM_001330096

NRXN1

16.48

0.50

5.04

0.98

protein_coding

Neurexin 1

XM_017011231

TCP10

16.48

0.50

5.04

0.98

protein_coding

t-complex 10

XR_929124

LOC105375935

14.12

0.50

4.82

0.97

lncRNA

Uncharacterized LOC105375935

NR_104037

UBE2C

23.54

0.87

4.76

0.99

protein_coding

Ubiquitin conjugating enzyme E2 C

NM_001014985

GLTPD2

12.94

0.50

4.69

0.97

protein_coding

Glycolipid transfer protein domain containing 2

NM_007200

AKAP13

12.94

0.50

4.69

0.97

protein_coding

A-kinase anchoring protein 13

NM_015055

SWAP70

12.94

0.50

4.69

0.97

protein_coding

Switching B cell complex subunit SWAP70

NR_123740

RIMKLB

12.94

0.50

4.69

0.97

protein_coding

Ribosomal modification protein rimK like family member B

NM_024093

C2orf49

0.50

13.90

− 4.80

0.97

protein_coding

Chromosome 2 open reading frame 49

XR_002956178

PARP8

0.50

13.90

− 4.80

0.97

protein_coding

Poly(ADP-ribose) polymerase family member 8

NM_207404

ZNF662

0.50

14.77

− 4.88

0.97

protein_coding

Zinc finger protein 662

NM_001184763

UHMK1

0.50

15.64

− 4.97

0.98

protein_coding

U2AF homology Motif kinase 1

XR_946261

LOC101927445

0.50

15.64

− 4.97

0.98

lncRNA

uncharacterized LOC101927445

NM_001008216

GALE

0.50

17.38

− 5.12

0.98

protein_coding

UDP-galactose-4-Epimerase

XR_944683

SMARCD1

0.50

17.38

− 5.12

0.98

protein_coding

SWI/SNF related

XR_001749246

LOC105369890

0.50

19.11

− 5.26

0.98

lncRNA

Uncharacterized LOC105369890

NR_146113

VPS8

0.50

19.98

− 5.32

0.98

protein_coding

VPS8 subunit of CORVET complex

XM_017026805

LOC390877

0.50

19.98

− 5.32

0.98

protein_coding

Adenylate kinase isoenzyme 1-like