Table 4 Distribution of addiction systems among transmissible plasmids encoding CTX-M genes and harboured by donor parental strains of clinical origin in Ethiopia.

From: Characterization of plasmids carrying blaCTX-M genes among extra-intestinal Escherichia coli clinical isolates in Ethiopia

CTX-M type ESBL with other β-lactamases

n

Addiction systems

pmeK

ccdAB

vagCD

hok-sok

pndAC

srnBC

totala

meanb

CTX-M-15

51

50

49

40

18

33

46

237

4.6

only CTX-M-15

2

2

2

2

0

1

2

9

4.5

 + TEM-1

7

7

7

6

3

6

6

35

5.0

 + OXA-1

12

13

12

11

6

9

12

63

4.8

 + TEM-1, OXA-1

29

28

28

20

9

17

26

128

4.4

Other group 1 CTX-Ms

17

16

14

11

6

10

16

73

4.3

 + TEM-1

4

3

3

1

0

2

4

13

3.3

 + OXA-1

4

4

3

4

2

3

4

20

5.0

 + TEM-1, OXA-1

9

9

8

6

4

5

8

40

4.4

Group 9 CTX-Ms

7

6

5

4

2

5

6

28

4.0

CTX-M-14 + TEM-1

1

0

0

0

0

0

0

0

0

only CTX-M-27

1

1

1

1

1

1

1

6

6.0

 + TEM-1

1

1

1

1

1

1

1

6

6.0

 + TEM, OXA-1

4

4

3

2

0

3

4

16

4.0

Total

75

72

68

55

26

48

68

337

4.5

  1. aRefers to the total number of isolates that had an identifiable addiction system encoded on a plasmid with defined CTX-M producing genes alone or in combination with alternative β-lactamase-encoding genes (non-ESBLs genes).
  2. bRefers to the average number of addiction systems encoded on a plasmid with defined β-lactamase-encoding genes; calculated as ‘total’ number of identified addiction systems divided by ‘n’ number of isolates containing a plasmid(s) with stated β-lactamase-encoding gene.
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