Table 4 Pregnancy outcomes after Frozen embryo transfers.

From: Features of chromosomal abnormalities in relation to consanguinity: analysis of 10,556 blastocysts from IVF/ICSI cycles with PGT-A from consanguineous and non-consanguineous couples

Variable

Total

Consanguine group

Non-consanguine group

p

N (%)

1660

364 (21.93%)

1296 (78.07%)

 

Endometrial preparation

0.099

 HRT

985

223 (64.8%)

762 (62.5%)

 NC

564

115 (33.4%)

449 (36.8%)

 Stimulated

14

6 (1.7%)

8 (0.7%)

Female age, n = 1660 (mean ± SD, range)

33.5 ± 5.43 (19–47)

32.5 ± 5.60

33.8 ± 5.46

< 0.001

Partner age, n = 1659 (mean ± SD, range)

37.1 ± 7.21 (21–80)

35.8 ± 5.65

37.5 ± 7.56

 < 0.001

AMH (ng/mL), n = 1417 (mean ± SD, range)

3.3 ± 3.05 (0.01–28.5)

3.3 ± 2.88

3.3 ± 3.0

0.422

BMI (kg/m2), n = 1635 (mean ± SD, range)

27.1 ± 4.87 (13.1–43.9)

27.9 ± 5.16

26.9 ± 4.80

0.001

Transfer day, n = 1660

0.670

 Day 5 (n, %)

1130 (68.1%)

251 (69.0)

879 (67.8)

 Day 6 (n, %)

509 (30.7%)

110 (30.2)

399 (30.8)

 Day 7 (n, %)

21 (1.2%)

3 (0.8)

18 (1.4)

Number of embryos transferred (mean ± SD)

1.4 ± 0.49

1.5 ± 0.50

1.4 ± 0.49

0.083

Pregnancy rate, n = 1660 (%)

1169 (70.4%)

261 (71.7%)

908 (70.1%)

0.544

Miscarriage rate, n = 1169 (%)

313 (26.8%)

70 (26.8%)

243 (26.8%)

0.985

Biochemical miscarriage rate, n = 1169 (%)

103 (8.8%)

21 (8.1%)

82 (9%)

0.621

Clinical miscarriage rate, n = 1169 (%)

183 (15.7%)

41 (15.7%)

142 (15.6%)

0.978

Live Birth Rate per pregnancy, n = 1169 (%)

856 (73.2%)

191 (73.2%)

665 (73.2%)

0.985

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