Figure 1 | Scientific Reports

Figure 1

From: Platelets from patients with myeloproliferative neoplasms have increased numbers of mitochondria that are hypersensitive to depolarization by thrombin

Figure 1

Increased mitochondria in platelets of MPN patients. (A) TEM images were used to count the number of mitochondria within 50 platelets per individual subject. A comparison between healthy donors (n = 16) and MPN patients (n = 23) of the number of mitochondria per platelet was done using categorized data ranging from 0 mitochondria/platelet to 20 mitochondria/platelet. Error bars at each point represent differences between individual subjects. (B) TEM images of 3 mitochondria (indicated with white arrows) in a healthy donor platelet (i) and 20 mitochondria in an ET patient platelet (ii). Confocal microscopy images of 2 mitochondria (in green) in a healthy donor platelet (iii) and 20 mitochondria in an ET patient platelet (iv).

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