Figure 2 | Scientific Reports

Figure 2

From: Platelets from patients with myeloproliferative neoplasms have increased numbers of mitochondria that are hypersensitive to depolarization by thrombin

Figure 2

TNFα is increased in MPN patients and inversely correlated with platelet mitochondrial mass. (A) The concentration of TNFα measured in plasma samples was higher in MPN patients than in healthy donors (median and 95% CI). (B) In MPN patients there was an inverse correlation between TNFα concentration and platelet mitochondrial mass (assessed as total number of mitochondria in 50 platelets in TEM images). Healthy donors (black circles), ET (squares), PV (diamonds), PMF (triangles), JAK2 V617F (red), CALR (blue), triple negative (green). P < 0.05 (*), Pearson correlation, P < 0.01 (**).

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