Table 2 AUC of the ROC curves of F for varying patch radius and binding affinity. The AUC of the ROC curves are computed using the binding and random regions Fs distributions. The binding region distributions are divided into three groups, according to the binding affinity \(B_a\) of their complex. Increasing values of the radius R defining the patches are tested. The complexes are part of the ’Affinity’ dataset.

From: Electrostatic complementarity at the interface drives transient protein-protein interactions

F

\(R=6\)

\(R=9\)

\(R=12\)

\(R=15\)

\(B_a<-9.0\)

0.54

0.55

0.51

0.54

\(-6.0<B_a<-9.0\)

0.67

0.67

0.65

0.65

\(B_a>-6.0\)

0.77

0.81

0.86

0.86