Figure 4
From: Wound healing responses of urinary extravasation after urethral injury
Post-surgical epithelial and mesenchymal histological structures were investigated by the expression of E-Cadherin (green) and Vimentin (red) in immune-fluorescence staining (Scale bar: 100 µm). The epithelial E-Cadherin expressions disappeared in both Group1 (urethral injury with urinary extravasation) and Group 2 (urethral injury without urinary extravasation) at POD1. As for mesenchymal histology of the Group1, the Vimentin expression disappeared at POD3 (white arrow in the second image from the left of the upper row). However, such mesenchymal expression was already recovered in POD3 in Group2 (yellow arrow in the second image from the left of the middle row). In Group1, the Vimentin expressions were gradually recovered in POD7-14, albeit the loss of mesenchymal sinusoidal structures (the third and fourth images from the left of the upper row). The urethral epithelium was thickened from POD3 (white arrowhead) in Group1.
