Table 1 In-vitro (Virtual Screening-VS) and in-vivo (Animal Model-AM) prediction of drug (QCT, EA, ZBN)-receptor (IL-10, TNF- α, COX-3) interaction based on docking and up-down regulation in animal screening.
From: Phytochemical mediated modulation of COX-3 and NFκB for the management and treatment of arthritis
- Up-regulation indicated by up arrow (
) while down-regulation by (
). Additional formation of bond with aromatic ring is represented by ($: π–π stacking bond) and (^: π–Cation bond).
) while down-regulation by (
). Additional formation of bond with aromatic ring is represented by ($: π–π stacking bond) and (^: π–Cation bond).