Figure 2

Percentage rat body weight change across gestation period relative to day 1 (D1) of pregnancy. Following drug/vehicle administration, rats in the normal pregnancy group (M−P−; n = 10) continued to show an increase in weight, while rats in the abortion group (M+P−; n = 10) showed significant weight loss, which was also observed in the unsuccessful reversal group (M+P+ (U); n = 3). Rats in the M+P+ group (mifepristone + progesterone / reversal, n = 13) displayed some weight loss followed by a recovery in weight and continued weight gain that paralleled the M−P− group (normal pregnancy). **p < 0.01, ***p < 0.001 (Relative to M−P−); ^#p < 0.05, ^###p < 0.001 (Relative to M+P+). Data is expressed as mean ± SEM. Arrow indicates day of drug/vehicle administration.