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Figure 3

From: Oxidative stress increases in liver of lactating rats after BPF-low-dose exposure: perinatal effects in the offspring

Figure 3

Effects of BPF administration on glutathione concentrations and oxidative stress biomarkers in liver from female and male PND6 offspring. (a) Concentration of reduced glutathione (GSH) in nmol/mg protein. b) Concentration of oxidized glutathione (GSSG) in nmol/mg protein. (c) GSSG/GSH ratio. (d) Malondialdehyde (MDA) content in nmol/mg protein. e) Lipid hydroperoxide (LPO) content in nmol/mg tissue. Data represent mean ± SD. n = 12 female PND6 pups; n = 12 male PND6 pups for each experimental group with two replicates for each sample (control, LBPF and HBPF). Statistical significance was determined by one-way ANOVA. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 compared to Control group. ∇∇P < 0.01; ∇∇∇P < 0.001, ∇∇∇∇P < 0.0001, LBPF vs. HBPF. ♦ LBPF Female vs. LBPF Male.

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