Table 2 Distribution of mecA and virulence fator genes in subgingival staphylococci strains isolated from individuals with distinct periodontal conditions.

From: Antimicrobial resistance and virulence of subgingival staphylococci isolated from periodontal health and diseases

Genes

Periodontal health (n = 42)

Gingivitis (n = 38)

Periodontitis (n = 149)

Predominant species

Total (n = 239)

mecA + 

3

4

18 (13#)

Sep, Sau, Scap, Sco, Ssci, Staphy

25

 Resistant ≥ 2 antimicrobials

2

1

10*

13*

 Resistant ≥ 3 antimicrobials

2

1

3

6*

 Resistant to Penicillin

3

3

12

18

 Resistant to Amoxicillin

3

3

10

16

 Resistant to Cefoxitin

2*

3*

6*

11*

Virulence factors

(n = 37)

(n = 31)

(n = 141)

 

(n = 209)

 groEL

33

22

119

All species

174*

 ebpS

7

6

39

Sep, Sau, Ssap, Swar, Scap, Sco, Ssci

52

 cna

8

12

43

Sep, Sau, Scap, Ssap, Swar, Sco, Ssci, Sho

63

 bbp

0

0

4

Sep, Sau

4

 luxF/luxS-pvl

0

2

10

12

 fnbA

1

1

8

10

 fnbB

1

2

25*

Sep, Sau, Ssap, Swar, Sho

28*

  1. #Periodontitis Stages III/IV; *Significant differences among groups (Chi-square test, p < 0.05); mecA (low affinity penicillin-binding protein 2A); ebpS (elastin-binding protein), cna (collagen-binding protein), fnbA and fnbB (fibronectin-binding proteins A and B), bbp (bone sialoprotein-binding protein), luxF/luxS-pvl (Panton–Valentine leukocidin), groEL (chaperonin of the heat shock protein family).
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