Table 2 Cortical symptoms and correspondence with increased THK5351 uptake lesions.
From: High sensitivity of asymmetric 18F-THK5351 PET abnormality in patients with corticobasal syndrome
Number of patients | Corresponding brain lesions | Increased THK uptake | Brain atrophy by MRI | Decreased brain perfusion by SPECT | |
|---|---|---|---|---|---|
Limb-kinetic apraxia | 13 | Contralateral precentral gyrus | 77% (10/13) | 62% (8/13) | 56% (5/9) |
Ideomotor apraxia | 10 | Left fronto-parietal lobes | 80% (8/10) | 70% (7/10) | 63% (5/8) |
Cortical sensory deficits | 7 | Contralateral postcentral gyrus | 71% (5/7) | 43% (3/7) | 60% (3/5) |
Speech and language impairment | 10 | Left frontal lobe | 90% (9/10) | 70% (7/10) | 63% (5/8) |
