Table 2 Binding free energy (KJ/mol) for acarbose and 8c.

From: Design, synthesis, in vitro, and in silico evaluations of benzo[d]imidazole-amide-1,2,3-triazole-N-arylacetamide hybrids as new antidiabetic agents targeting α-glucosidase

Complex

Van der Waals energy

Electrostatic energy

Polar solvation energy

SASAa energy

Binding energy

8c

− 166.2

− 27.3

138.0

− 19.6

− 75.1

Acarbose

− 219.9

− 30.1

163.8

− 29.5

− 115.7

  1. aSolvent-accessible surface area.
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